Meridia diet medicine
Among other effects, GLP-1 delays gastric emptying and promotes a feeling of satiety. It was not until the 1920s and 1930s that new treatments began to appear. Dexfenfluramine (Redux) was developed in the mid-1990s as an alternative to fenfluramine with less side-effects, and received regulatory approval in 1996. He prescribed elixirs of laxatives and purgatives, as well as heat, massage, and exercise. Orlistat (Xenical) the most commonly used medication to treat obesity and sibutramine (Meridia) a medication that was recently withdrawn due to cardiovascular side effects. Overdose, although rare, lead to a rise in body temperature and, ultimately, fatal hyperthermia. Lorcaserin (Belviq) was approved June 28, 2012 for obesity with other co-morbidities. Appetite suppression- Catecholamines and their derivatives (such as phentermine and other amphetamine -based drugs) are the main tools used for this, although other classes of drugs such as anti-depressants and mood stabilizers have been anecdotally used for appetite suppression (see: bupropion and topiramate ). Orlistat (Xenical) reduces intestinal fat absorption by inhibiting pancreatic lipase. Drawbacks of Byetta include that it must be injected subcutaneously twice daily, and that it causes severe nausea in some patients, especially when therapy is initiated. (February 2015) ( Learn how and when to remove this template message ). This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day. Current and potential anti-obesity drugs may operate through one or more of the following mechanisms. Some side-effects of using Orlistat include frequent, oily bowel movements ( steatorrhea ). They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. In the past, it was noted by the US that Meridia was a harmless drug for fighting obesity. The most significant side effect was a sensation of warmth, frequently with sweating. Based on its effectiveness for hypothyroidism, thyroid hormone became a popular treatment for obesity in euthyroid people. Sibutramine may increase blood pressure and may cause dry mouth, constipation, headache, and insomnia.
Sibutramine (Reductil or Meridia) is an anorectic or appetite suppressant, reducing the desire to eat. Exenatide (Byetta) is a long-acting analogue of the hormone GLP-1, which the intestines secrete in response to the presence of food. A somewhat similar drug, Symlin, is currently available for treating diabetes and is in testing for treating obesity in non-diabetics. Meanwhile, phentermine had been FDA approved in 1959 and fenfluramine in 1973. Pramlintide (Symlin) is a synthetic analogue of the hormone Amylin, which in normal people is secreted by the pancreas in response to eating. Rimonabant (Acomplia) is a recently developed anti-obesity medication. Byetta is recommended only for patients with Type 2 Diabetes. Rimonabant (Acomplia), a second drug, works via a specific blockade of the endocannabinoid system. The first described attempts at producing weight loss are those of Soranus of Ephesus, a Greek physician, in the second century AD. But if fat in the diet is reduced, symptoms often improve. This remained the mainstay of treatment for well over a thousand years. The OTC fiber supplements glucomannan and guar gum have been used for the purpose of inhibiting digestion and lowering caloric absorption. Some, but not all, patients find that they lose substantial weight when taking Byetta. Amphetamines (marketed as Benzedrine) became popular for weight loss during the late 1930s. For example, Orlistat (also known as Xenical and Alli) blocks fat breakdown and thereby prevents fat absorption. Unsourced material may be challenged and removed. Anti-obesity medication or weight loss drugs are all pharmacological agents that reduce or control weight. Typical regimens included stimulants, such as amphetamines, as well as thyroid hormone, diuretics, digitalis, laxatives, and often a barbiturate to suppress the side effects of the stimulants. Please help improve this section by adding citations to reliable sources.
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